In Vitro Immunology Scientist

Cambridge, Massachusetts, United States Full-time

 In Vitro Immunology Scientist 


Evelo Biosciences, founded by Flagship VentureLabs has established the leading therapeutics discovery and development based on the human immuno-microbiome. We are developing onco-microbials for the treatment of cancer and immuno-microbials for the treatment of autoimmune and inflammatory diseases.


We are seeking talented and dedicated Scientists, who are  interested in joining a highly dynamic and intellectually challenging team. This exciting role will afford Scientists the opportunity to be intimately involved in the implementation of cutting-edge research programs in a multifunctional biology laboratory.   Successful candidates will posses expertise in immunology and/or immuno-oncology and a proven ability to multi-task within scope. 


Primary responsibilities:


- Design and conduct in vitro immune cell-based assays for screening, discovery, and mechanistic analysis of microbial drug candidates

- Design and implement rigorous ex vivo assays to understand immunological mechanism of action 

- Develop and implement multi-parameter flow cytometry-based immune phenotyping assays, cell sorting assays, and multiplex cytokine profiling assays

- Actively participate on project teams and collaborate across interdisciplinary R&D programs

-Independently design rigorous experiments, interpret data, and communicate findings in well-articulated presentations


Desired capabilities, skills and experience:


- Candidates must have a background in immunology, immuno-oncology, drug discovery with experience in microbiome field a plus

- Proficient in flow cytometry techniques, cytokine/chemokine profiling on Luminex or similar platform

- Experience with primary mammalian cell culture, cell proliferation assays, and/or metabolic assays

- Experience with ex vivo rodent sample processing, including RNA/DNA extraction, immunophenotyping, and immunohistochemistry

- Highly motivated and results driven individual with a passion for working in a fast-paced and evolving organization

- Strong oral and written  communication as well as excellent collaboration & interpersonal capabilities

- Outstanding team player with ability to work in groups as well as independently 

- Adept at problem solving


Education and experience requirements:


- Ph.D. in immunology or related field

- 3-5 years of relevant experience in biopharmaceutical industry strongly preferred