Next Generation Sequencing Scientist/Associate Scientist

Cambridge, Massachusetts, United States

Next Generation Sequencing Scientist

This is an outstanding opportunity to join a fast-paced company in a new exciting field of medicine.  Evelo Biosciences is dedicated to improving the lives of patients globally through the development of monoclonal microbials.  As a member of the Evelo team, you will be a vital part of helping to shape Evelo’s vision: in transforming therapies through a new modality of medicines.

Evelo Biosciences is seeking an experienced NGS Scientist to join our talented and dedicated team of scientists and engineers in changing the lives of patients around the world in a fast-paced environment. The successful candidate will drive the use of NGS to advance cutting-edge programs and the discovery and validation of novel targets and biomarkers in preclinical and clinical drug discovery and development. Must have a deep passion for improving health outcomes for patients.




The successful candidate will advance Evelo’s pipeline in discovery, preclinical and clinical stages by accomplishing the following:

  • Collaborate with therapeutic area scientists and clinical researchers to design fit for purpose NGS experiments
  • Prepare samples, develop methods for sample preparation, and develop best practices to ensure sample quality
  • Use a combination of in house hardware and strategic partnerships to deliver NGS data in a time and cost-efficient manner
  • Perform primary processing and analysis of sequencing data to assess parameters of sequencing quality
  • Share and contribute scientific and technical know-how and experience with team members



  • Experience in operating an Illumina sequencing platform (MiSeq or HiSeq), nucleic acid isolation from prokaryotic and eukaryotic sources, and library preparation
  • Minimum of 3 years of post-graduate or biotech/pharma experience in standard molecular biology and NGS techniques
  • Proficient in troubleshooting, protocol development, and vendor management
  • Demonstrated ability to work collaboratively with research project teams
  • Dynamic, flexible, well-organized, pro-active, collaborative-minded individual, passionate about improving health outcomes for patients around the world



About Evelo

Evelo Biosciences is dedicated to improving the lives of patients globally through the development of a new modality of medicines – monoclonal microbials. Monoclonal microbials are orally delivered medicines that modulate systemic immunology and biology through direct interactions with human cells in the gut. These new medicines are broadly applicable across many diseases – including autoimmune, immunoinflammatory, metabolic, neurological, neuroinflammatory diseases and cancer. Monoclonal microbials have the potential to fundamentally change traditional models of drug discovery and development. By finding and selecting naturally occurring monoclonal microbials with defined therapeutic effects, Evelo can improve the speed, cost and success of drug discovery and development. Evelo’s platform enables pharmacological intervention at all stages of disease with naturally occurring, safe and effective monoclonal microbials. Evelo Biosciences was conceived and created within VentureLabs®, Flagship Pioneering’s institutional innovation foundry, and launched by Flagship in 2015. For more information, please visit


Apply for this opening at