Computational Scientist

Cambridge, Massachusetts, United States Full-time

Computational Scientist


Evelo Biosciences is seeking an experienced Computational Scientist to join our talented and dedicated team of scientists and engineers in changing the lives of patients around the world in a fast-paced environment. The successful candidate will drive the use of computational approaches to advance cutting-edge programs and the discovery and validation of novel targets and biomarkers in preclinical and clinical drug discovery and development. Must have a deep passion for improving health outcomes for patients.




The successful candidate will advance Evelo’s pipeline in discovery, preclinical and clinical stages by accomplishing the following:

  • Collaborative with therapeutic area scientists and clinical researchers in applying state-of-the art informatics and data mining approaches
  • Design and execute on the analysis of in vivo and in vitro experiments
  • Design and execute on the analysis of in silico experiments
  • Identify and evaluate external collaborators, novel methods and emerging expertise
  • In-depth characterization of cellular and human microbiome responses in preclinical and clinical models
  • Share and contribute scientific and technical know-how and experience with team members



  • PhD. in a relevant scientific discipline or technology area, particularly in Computational Biology, Computer Science, Data Science
  • In-depth knowledge and extensive hands-on experience with genomics, metagenomics, microbiome or electronic medical records
  • Minimum of 5 years of post-graduate or biotech/pharma experience in analyzing large data sets with advanced analytics approaches
  • Hands-on experience with scientific computing capabilities including high performance computing (HPC), bioinformatics pipelines, natural language processing and machine learning
  • Versed in traditional and emerging mathematics and methods to model high dimensionality data sets
  • Knowledge of the pharmaceutical drug discovery and development process with a relevant track record, including preclinical and clinical drug development
  • Proven track record of scientific accomplishment and contributions to the field of computational sciences
  • Exceptional scientific reporting and presentation skills in translating complex statistical methods into readily understood and valuable results
  • Demonstrated ability to work collaboratively with research project teams and clinical development teams
  • Dynamic, flexible, well-organized, pro-active, collaborative-minded individual passionate about improving health outcomes for patients around the world